Ophthalmology in China ›› 2015, Vol. 24 ›› Issue (2): 73-75.doi: 10. 13281/j. cnki. issn.1004-4469. 2015. 02. 001

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Molecuar genetic analysis in the diagnosis for sporadic patients with optic neuropathies

LI Yang   

  1. Beijing Institute of  Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of
    Ophthalmology and Visual Science, Beijing 100005, China
  • Received:2015-02-18 Online:2015-03-25 Published:2015-04-06
  • Contact: LI Yang，Email：yanglibio@aliyun.com

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Abstract: Optic neuropathies are groups of complex diseases. Leber’s hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are responsible for parts of cases with unknown reason optic neuropathies and sometimes lack to family history. Therefore, it’s very important to do genetic analysis of LHON and ADOA for this kind of patients in order to avoid misdiagnosis or missed diagnosis. (Ophthalmol CHN, 2015, 24: 73-75)

Key words: optic atrophy/etiology, Leber’s hereditary optic atrophy, autosomal dominant optic atrophy, genic mutation